Detalhe da pesquisa
1.
Helical ordering of envelope-associated proteins and glycoproteins in respiratory syncytial virus.
EMBO J
; 41(3): e109728, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34935163
2.
Phase 3 randomized trial of mavorixafor, CXCR4 antagonist, in WHIM syndrome.
Blood
; 2024 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38643510
3.
Dissecting the roles of Cse1 and Nup2 in classical NLS-cargo release in vivo.
Traffic
; 21(10): 622-635, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32734712
4.
Distinct effects on mRNA export factor GANP underlie neurological disease phenotypes and alter gene expression depending on intron content.
Hum Mol Genet
; 29(9): 1426-1439, 2020 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32202298
5.
Function of the Nuclear Transport Machinery in Maintaining the Distinctive Compositions of the Nucleus and Cytoplasm.
Int J Mol Sci
; 23(5)2022 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35269721
6.
Polyadenylation and nuclear export of mRNAs.
J Biol Chem
; 294(9): 2977-2987, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30683695
7.
Effect of setmelanotide, a melanocortin-4 receptor agonist, on obesity in Bardet-Biedl syndrome.
Diabetes Obes Metab
; 22(11): 2133-2140, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32627316
8.
Structure and Function of the TREX-2 Complex.
Subcell Biochem
; 93: 461-470, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31939161
9.
Structure of the Sac3 RNA-binding M-region in the Saccharomyces cerevisiae TREX-2 complex.
Nucleic Acids Res
; 45(9): 5577-5585, 2017 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28334829
10.
Structural basis for the dimerization of Nab2 generated by RNA binding provides insight into its contribution to both poly(A) tail length determination and transcript compaction in Saccharomyces cerevisiae.
Nucleic Acids Res
; 45(3): 1529-1538, 2017 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28180315
11.
Structural basis for Pan3 binding to Pan2 and its function in mRNA recruitment and deadenylation.
EMBO J
; 33(14): 1514-26, 2014 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24872509
12.
Improving public health by improving clinical trial guidelines and their application.
Eur Heart J
; 38(21): 1632-1637, 2017 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28329235
13.
Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export.
Mol Cell
; 33(6): 727-37, 2009 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19328066
14.
Domain organization within the nuclear export factor Mex67:Mtr2 generates an extended mRNA binding surface.
Nucleic Acids Res
; 43(3): 1927-36, 2015 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25618852
15.
The principal mRNA nuclear export factor NXF1:NXT1 forms a symmetric binding platform that facilitates export of retroviral CTE-RNA.
Nucleic Acids Res
; 43(3): 1883-93, 2015 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25628361
16.
Development of Cell-Permeable, Non-Helical Constrained Peptides to Target a Key Protein-Protein Interaction in Ovarian Cancer.
Angew Chem Int Ed Engl
; 56(2): 524-529, 2017 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27918136
17.
Efficacy and safety of once-weekly GLP-1 receptor agonist albiglutide (HARMONY 2): 52 week primary endpoint results from a randomised, placebo-controlled trial in patients with type 2 diabetes mellitus inadequately controlled with diet and exercise.
Diabetologia
; 59(2): 266-74, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26577795
18.
The Sac3 TPR-like region in the Saccharomyces cerevisiae TREX-2 complex is more extensive but independent of the CID region.
J Struct Biol
; 195(3): 316-324, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27422657
19.
Structural and calorimetric studies demonstrate that the hepatocyte nuclear factor 1ß (HNF1ß) transcription factor is imported into the nucleus via a monopartite NLS sequence.
J Struct Biol
; 195(3): 273-281, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27346421
20.
Structural basis for binding the TREX2 complex to nuclear pores, GAL1 localisation and mRNA export.
Nucleic Acids Res
; 42(10): 6686-97, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24705649